I have been taking anti-depressants and SSRI's since I was around 14, I'm 25 now.. I have tried Zoloft, Lexapro, Celexa, Busbar, Paxil, Hydroxyzine, and Wellbutrin and they all either made my depression and anxiety either worse or made me not care about anything in my life. (Not saying it does help some folks, it just didn't help me.) I have been taking a gram of Kratom twice a day for over a year and I have felt more better about my life and my depression is almost completely gone. It has been a legit lifesaver for me. I weaned myself off of paxil around 6 months ago and it was the worst withdrawal I have ever went through with a SSRI. Kratom helped it alot though. I just wanted to share my story. Kratom can help depression and anxiety so much.